Ok, that may sound important, but how do I make this digestible on a practical scale? The graph below shows the probability that a certain condition has its roots in mitochondrial dysfunction. There are quite a few here and likely many more we don’t fully understand yet. The point is that mitochondria may not seem that important, but they are. They not only make energy, but play a role in cellular communication, signaling, immunity, and apoptosis (turning off and killing rogue cells or dying cells-often known as autophagy, but in the mitochondria, it is known as mitophagy). The good news is that there are practical ways to support mitochondria, improve function and increase longevity.
“A large amount of adenosine triphosphate (ATP) must be produced by the mitochondria every second of every day because ATP cannot be stored. This function is so important that mitochondria can take up as much as 25% of the cell volume. Cells contain from 1000 to 2500 mitochondria. The average cell uses 10 billion ATP per day, which translates to the typical adult needing 3.0 × 1025 ATP (I am publishing these numbers with some trepidation as the research is surprisingly inconsistent about exactly how much ATP a cell needs). To accomplish this prodigious feat, each ATP needs to be recycled from ADP 1000 times per day. Because the body cannot store ATP, the mitochondria must function consistently all the time. At any given time there are about 250 g of ATP in the cells. This represents about 4.25 watts, the equivalent of the energy in an AA battery. Every day, a healthy person produces a remarkable 1200 watts. Because the brain uses 70% of ATP, this helps explain the strong correlation between mitochondrial dysfunction and neurodegeneration.” Dr. Joe Pizzorno, ND quoted in the Integrative Medicine: A Clinician’s Journal
So right off the bat, we can see that mitochondria play a role in constantly making energy for us and the cells that contain the most mitochondria are in the brain! The heart, liver, kidneys, and ovaries are at close seconds. Many drugs have been taken off the market due to their mitochondrial toxicity, which caused a plethora of disease symptoms in patients.
Notable best mention is: aging- Recently, considerable progress in understanding basic mitochondrial genetics and in identifying acquired mitochondrial DNA mutations in aging has been made. Furthermore, the creation of mitochondrial DNA-mutator mice has provided the first direct evidence that accelerating the mitochondrial DNA mutation rate can result in premature aging, consistent with the view that loss of mitochondrial function is a major causal factor in aging. Yes, mitochondrial damage is inevitable and unavoidable.
Some necessary cofactors and vitamins used in ATP production (that you should use in your protocols) include:
Here are Dr. Jess’s favorite ATP-boosting supplements:
Here are Dr. Jess’s Favorite ATP-boosting activities:
You can heal by becoming your own best doctor.
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